Krista Rule Wigginton

The Wigginton research group examines the source and fate of emerging contaminants in aqueous systems.  Part of our focus is on human pathogenic viruses; in particular, we 1) seek improved virus detection methods, 2) aim to better understand the types and concentrations of human pathogenic viruses that exist in our daily environment, and 3) utilize a range of biomolecular and analytical chemistry tools to link virus particle characteristics to observed behaviors in natural and engineered environments. Our group also studies how drinking water and wastewater treatment processes can be modified to remove emerging chemical and biological contaminants.

• Miller Faculty Scholar, U-M College of Engineering, 2022
• The Paul L. Busch Award, 2018
• NSF CAREER Award, 2014-2018
• NSF BRIGE Award 2012
• American Water Works Association Dissertation Award, 2010
• NSF International Research Postdoctoral Fellow, 2009-2011
• ACS C. Ellen Gonter Environmental Chemistry Award, 2008
• NSF Graduate Fellowship, 2003

• Rockey, N. C., Henderson, J. B., Chin, K., Raskin, L., & Wigginton, K. R. (2021). Predictive modeling of virus inactivation by UV. Environmental Science & Technology, 55(5), 3322-3332.
• Crossette, E., Gumm, J., Langenfeld, K., Raskin, L., Duhaime, M., & Wigginton, K. (2021). Metagenomic quantification of genes with internal standards. MBio, 12(1), e03173-20.
• Graham, K. E., Loeb, S. K., Wolfe, M. K., Catoe, D., Sinnott-Armstrong, N., Kim, S., Yamahara, K.M., Sassoubre, L. M., Mendoza L.M., Roldan-Hernandez, L., Langenfeld, K., Wigginton, K. R.,  Boehm, A. B. (2020). SARS-CoV-2 RNA in wastewater settled solids is associated with COVID-19 cases in a large urban sewershed. Environmental science & technology, 55(1), 488-498.
• Ye, Y., Chang, P. H., Hartert, J., & Wigginton, K. R. (2018). Reactivity of enveloped virus genome, proteins, and lipids with free chlorine and UV254. Environmental science & technology, 52(14), 7698-7708.
• Chang, P. H., Juhrend, B., Olson, T. M., Marrs, C. F., & Wigginton, K. R. (2017). Degradation of extracellular antibiotic resistance genes with UV254 treatment. Environmental Science & Technology, Vol. 51, pp. 6185–6192.
• Ye, Y., Ellenberg, M., Graham, K, Wigginton K. (2016) “Survivability, partitioning, and recovery of enveloped viruses in untreated municipal wastewater.” Environmental Science & Technology, Vol. 50, pp. 5077-5085.